The TarHelium
   Volume 38, Issue 2                                                                                                     October, 2007

 Nicolle S. Tulve,

 Judi Price,
Copy Editor

 M. Pasquinelli,
& Address Information acs logo


  A. Tonelli, Chair
  J. Brown, Chair-Elect
  M. Pasquinelli, Secretary
  J. T. Bursey, Treasurer


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The TarHelium is a publication of the North Carolina Section of the American Chemical Society.
-- for more information --

What's in this Issue


    Ivan D. Jones
    Frederick P. Pike
    John Geldart Aston
    W. N. Stoops


The NC ACS Local Section will again participate in the North Carolina State Fair. Similar to 2006, we will have both a chemistry booth and present chemistry stage shows in the "Our Land, Our Legacy" tent. We need you to volunteer! All members of the Local Section are encouraged to participate. New volunteers will be paired with seasoned volunteers who have worked the fair in previous years. Volunteers will receive free admission to the Fair and also have the chance to earn a State Fair t-shirt. Please read the details below.

Ready to Volunteer: Contact the Organizer,
or fill out the online form:
When: October 12-21, 2007
Where: State Fairgrounds, Raleigh, NC.
Additional information about the NC State Fair is available online at:
About Our Stage Show: The times of the presentations have not been assigned yet, but we are expecting at least four presentations each day. Volunteers are asked to help with managing the crowds, answering questions about the presentations, and presenting stage shows (if interested).

Admission to the Fair is free for all volunteers. We will also have access to a limited number of parking passes.

Company Logos: If employees from your company volunteer, we will be happy to display your company logo as part of a PowerPoint presentation given during the stage shows.
Questions: Contact the Organizer: Bill Switzer
([email protected])


THANKS go to Sarah Allen and her colleagues for their significant efforts in organizing our local High School Chemistry Olympiad Program!


    • John Hines

    Councilor (3 openings):

    • Laura Sremaniak (incumbent)
    • Bryce Chaney
    • Sara Paisner

    Alternate Councilor (3 openings):
    • Ken Tomer (incumbent)
    • Keith Levine
    • Alan Tonelli


    • Melissa Pasquinelli



John Hines received his B.S. degree in Chemistry from Virginia Polytechnic Institute in 1969 and his Ph.D. in Organic Chemistry from the University of Georgia in 1974. After a 1-year Post-Doc at the University of Georgia, he joined the staff at RTI International in the area of analytical chemistry, specifically high performance liquid chromatography and capillary gas chromatography. At RTI, he has worked in both environmental and pharmaceutical analysis but for the past 20 years has focused primarily on the areas of characterization/analysis supporting drug development for commercial and government programs. He is currently Senior Laboratory Manager of the Pharmaceutical Sciences Laboratory and Principal Investigator for multi-year research programs providing broad-range analytical support for development of new therapeutics for both NIDA and NCI. His current research interests cover all areas of separation science (HPLC, CGC, CE, IC, etc.) and ancillary characterization methods (MS, NMR).

John has been a member of the Triangle Chromatography Discussion Group (the TCDG) steering committee for over 20 years and has served several times as secretary, treasurer, program chair, President, and in all of the various areas of the TCDG symposium planning. He has also served the NCACS on the 1998 and 2004 SERMACS organizing committees where he was Exhibit Chair. As liaison for the TCDG, he has served more than 10 years on the NCACS Scholarship Committee. In 1999, he received the Marcus E. Hobbs Award for Service to the Local Section.



Dr. Laura Sremaniak received her B.S. degree in Chemistry from the University of South Carolina in 1991, and a Ph.D. in theoretical chemistry from the University of North Carolina at Chapel Hill in 1996. She joined the chemistry faculty at North Carolina State in 1996 and is now a Teaching Associate Professor. In addition to teaching physical chemistry, she is implementing the Computational Chemistry Laboratory courses she developed for the BS curriculum. Her research interests include electronic structure calculations of adsorbates on metal, oxide, and zeolite surfaces. Laura has been an ACS member since 1990 and is currently a Councilor. At the national level she serves on the Women Chemists Committee (WCC) and recently co-founded a local WCC group. She also serves on the local advisory subcommittee for Project Seed, and has assisted with the NC State Fair and the NC Local Section Meetings.


Upon graduating cum laude with a B.S. in biochemistry and departmental honors from the University of North Carolina - Charlotte, Mr. Chaney pursued a career in the medical device industry working for BD Technologies, the corporate research and development center for Becton Dickinson & Co., located in Research Triangle Park, NC. Initially, Mr. Chaney worked as a member of the Worldwide Medical Toxicology team where he learned and practiced FDA-compliant medical device testing procedures. Bryce then transitioned into a newly formed research group focused on developing novel cellular technologies and therapeutics. Mr. Chaney was responsible for developing novel biomaterial coatings as well as for identifying and integrating automated high-throughput screening systems used for culturing and testing primary human isolates and stem cells. Since then, the Cell & Tissue Technologies team has forged partnerships with numerous external companies in the areas of diabetes therapies, drug discovery, and stem cell therapeutics. Mr. Chaney later transitioned into the BD intellectual property department where he filled the role of IP Liaison. Bryce was responsible for managing and developing patent strategies for research teams focused in the areas of biological sensing systems and stem cell technologies.

Today, Bryce works as the Business Development Manager at Cirrus Pharmaceuticals, Inc., located in Research Triangle Park. Cirrus is a CRO focused on pharmaceutical formulations and analytical method development with particular strengths in inhalation, parenteral, and oral product development.

Mr. Chaney graduated from UNC Chapel Hill's Kenan-Flagler Business School with an M.B.A. in September 2007. Mr. Chaney is an author or presenter of nine publications and seven published or pending patents. He grew up in Chillicothe, OH where he was actively involved in high school athletics and outdoor activities. Bryce is an Eagle Scout and enjoys international travel and high-adventure activities. Bryce is the oldest of three children and is now married to his high school sweetheart, Erin, who is a medical resident at Duke University's Anesthesiology program.


Dr. Paisner received her A.B. at Dartmouth College, and her Ph.D. at the University of California at Berkeley. During her postdoctoral research at UNC- Chapel Hill, she worked on developing new types of low K dielectric materials. She then moved to GE's Global Research Center where she worked on a variety of projects focusing on developing new materials for the electronics industry. While at GE, Dr. Paisner utilized a variety of technologies, including nanotechnology, to develop new thermal and encapsulating materials.

Dr. Paisner is currently a Senior Scientist in the Microelectronics Technology Group at Lord Corporation in Cary, NC. She leads a variety of projects focused on developing Lord Corporation's next generation of thermal interface gels, greases and adhesives for the microelectronics industry. Dr. Paisner is the author of a variety of articles in peer reviewed journals, along with 4 patents and a book chapter, and is an active member of the American Chemical Society



Kenneth Tomer is a Senior Investigator at NIEHS and is head of the Mass Spectrometry Workgroup in the Laboratory of Structural Biology. He received his B.S. degree in chemistry from Ohio State University in 1966 and his Ph.D. in organic chemistry from the University of Colorado in 1970. After one year of postdoctoral study at the H.C. ├śrsted Institute (University of Copenhagen) and Stanford University (with Carl Djerassi), he held positions as Assistant Professor of chemistry (Brooklyn College/City University of New York) and Research Assistant Professor (University of Pennsylvania Medical School) before joining RTI from 1977-1981. From 1981 to 1986, Ken was Assistant/Associate Director of the Midwest Center for Mass Spectrometry and Associate Research Professor at the University of Nebraska. In 1986, he joined NIEHS as a Senior Investigator. In addition to his current position at NIEHS, he is an Adjunct Professor in the Oral Biology Program of the UNC School of Dentistry and has held visiting positions at Konstanz University in Germany and the University of Aveiro in Portugal.

Ken was appointed as Alternate Councilor in 2004. Ken has served as a co-chair of the Triangle Area Mass Spectrometry (TAMS) Discussion Group since 1988. He has most recently organized the symposium "Protein Characterization by Mass Spectrometry" at the 2004 Southeast Regional ACS meeting.

Ken's research interests are focused on the application of mass spectrometry to structural studies of proteins and protein interactions, to determination of epitopes viral and bacterial proteins recognized by antibodies against these infectious agents, and to proteomics. He has co-authored approximately 275 publications and served on the editorial boards of Biological Mass Spectrometry, Journal of the American Society for Mass Spectrometry, Journal of Capillary Electrophoresis and Biomolecular Engineering.


Keith E. Levine currently serves as a manager in RTI International's Trace Inorganics Department. In this capacity, he has nearly a decade of experience leading research projects focusing on the determination of trace elements in a wide variety of sample matrices. Since 2003, he has served the Inorganic Analysis Task Leader on RTI International's chemistry support contract with the National Toxicology Program.

Keith served as Editor of the North Carolina Section's newsletter, the TarHelium, from 2003 through 2006. For his service to the Section in this role, he was presented with the Section Chair award at the end of his tenure. Prior to joining RTI International, Keith received his B.S. in Chemistry from the University of Florida in 1994, and his Ph.D. in Analytical Chemistry from Wake Forest University in 1998. He currently resides in Durham with his wife and their three children.


Alan Tonelli received a B.S. in Chemical Engineering from the University of Kansas in 1964 and a Ph.D. in Polymer Chemistry from Stanford in 1968, where he was associated with the late Professor Paul J. Flory. He was a member of the Polymer Chemistry Research Department at AT&T-Bell Laboratories, Murray Hill, N.J. for 23 years, and in 1991 joined the Fiber and Polymer Science Program in the College of Textiles at North Carolina State University in Raleigh, NC, where he is currently the INVISTA Prof. of Fiber & Polymer Chemistry.

His research interests include the conformations, configurations, and structures of synthetic and biological polymers, their determination, principally by NMR, and establishing their effects on the physical properties of polymer materials. Most recently, the formation of and coalescence from inclusion compounds (ICs) formed between cyclodextrin (CD) hosts and polymer guests have been utilized to nanostructure bulk polymers, including homopolymers and their blends and block copolymers. In addition, small-molecule guest-CD host-ICs and -rotaxanes, and the covalent incorporation of CDs into polymers both during and subsequent to their syntheses, have been used to improve the delivery of additives to polymer materials



Dr. Melissa Pasquinelli has been serving as Secretary of the NC ACS since February 2007 after being appointed to the position. She is an Assistant Professor in Fiber and Polymer Science at North Carolina State University in the Department of Textile Engineering, Chemistry, and Science. Her research expertise is in the development and application of molecular simulation techniques that predict how molecular structures and the dynamics of molecular systems relate to their functional roles. She uses this experience to derive structure-function relationships for small molecules and macromolecules (i.e., polymers and proteins) in diverse areas including human health, nanomaterials, systems biology, functional textiles, and biomedical engineering. Prior to joining NC State, Dr. Pasquinelli completed two postdoctoral positions; she worked for two years as a Computational Chemist with the Office of Research and Development at the U.S. Environmental Protection Agency in the National Center for Computational Toxicology, and she also received postdoctoral training at Duke University with Prof. David Beratan. She received her Ph.D. in theoretical chemistry from Carnegie Mellon University in 2002 and her B.S. in chemistry with honors in 1996 from Seton Hill University in Greensburg, PA. She is originally from Saint Marys, PA, which is near the beautiful Allegheny National Forest. In her spare time, Dr. Pasquinelli enjoys exploring the outdoors, volunteering, playing cards, listening to music, and spending time with her family, friends, and pets.



Please place your ballot into an envelope and place the plain, sealed envelope into an envelope. The outer envelope must be signed across the seal, and your name printed so that the Nominating Committee can verify your membership.

Please send your ballot to:

    NC ACS Local Section
    c/o Sol Levine
    1307 Legacy Green Ave.
    Wake Forest, NC 27587

To print the just the ballot, select ballot - then using the "File" menu, select "Print".


Taurine Taurine, or 2-aminoethanesulfonic acid, is the ingredient du jour in energy drinks (i.e., Red Bull). It was first isolated from Ox bile (named for Taurus in Latin). It is a major component of bile and found in animal muscle tissue. Scientists are pursing its potential medicinal uses, which were discovered in part because cats cannot produce taurine and are subject to severe ailments when it is absent from their diet.


Duke University
October 3, 2007
-Coordinated by Ken Lyle

Click on thumbnail for full-sized picture
View from the Audience Rainbow Connection Mimi and her smoothie
Luminol Independence Day Fountains  
Mentos-Coke Chelsea's balloon  


Frank Ivy Carroll
Henry O. Colomb
Forrest William Getzen
Gordon G. Hammes
Arthur Walker Lockwood
Royce W. Murray
Thomas W. Olcott
Richard A. Palmer
William D. Timmons
Charles Tomasino
Frank Wood
Donald Lee Wright
Donald T. Forman
Sami Assad Halaby
Stanley Lester Kopczynski
Paul Joseph Kropp
Vsevolod S. Mihajlov
Walter Peter Miller
David Lee Morrison
Harvey Pobiner
Jack Preston
Stuart Reid
Paul Raphael Resnick
Michael Herbert Theil
John E. Barry
Andrew Howard Nickolaus
John Earl Sigsby
Vernon Eugene Summerfelt
Lilia Beauchamp
Barbara Blair
Robert Newcomer Eby
Lewis Hagood Owen
Ahmad Sam
Roman Slysh
Thomas Edward Walker
Everett S. Whitehead
Carl Lee Williams
William E Wilson
James Benjamin Borden
Henry Lien Hsieh
Laurance A. Knecht
Margaret M. Layton
Ralph Edward Peterson
R. O. Beauchamp
Roy L. Bennett
Chicita F. Culberson
Robert Ellery Fulmer
Harvey D. Ledbetter
William F. Little
Arnold Lawrence McPeters
Paul N. Strother
Ronald C. Greene
Richard G. Hiskey
Gunther C. Holsing
Edward A. Tyczkowski
Henry L. King
G. Gilbert Long
Eva G. McKenna
Edmund Mendell
Marjorie S. Remick
Edward A. Rick
Edmund H. Albrecht
Richard Pierson Buck
S. Robert Collins
John A. Durden
Alfred H. Ellison
George C. Harrison
Donald Lee Heywood
Abraham M. Kotliar
David T. Manning
Leonard Pierce
Richard Enos Wilson
Harry C. Allen
Ralph Harlan Burroughs
Howard G. Clark
William Twitty Donaldson
Willard Max Gentry
David A. Gordon
William Gilbert Lloyd
Rudolph Pariser
Paul S. Stenbuck
Winfield Paul Cowgill
John Anthony Cuculo
William F. Durham
Arthur Page Gough
Grannis Samuel Johnson
Peter Ramsey Johnston
Joseph Knoll
Paul Virgil Meyer
James E. Murphy
Kenneth C. Waldo
Alex Anthony Arcus
Harry Byron Keck
Stephen Joseph Metro
Eugene Moriarty
Frances M. Richardson
Mathias H .J. Weiden
Willis C. Wooten
Kenneth Orion Beatty
Benjamin H. Carpenter
Ernest L. Eliel
William F. Hamner
William Cecil Hunt
Virginia C. Menikheim
William J. Moran
Elmer E. Most
Robert G. Parr
John Warren Sloan
Thomas A. Bell
Horace Dean Brown
George C. Daul
Frank H. Field
John R. Huizenga
Louis Dubose Quin
Leo W. Ziemlak
James H. Boothe
Frank W. Melpolder
James W. L. Monkman
Walter C. Saeman
Edward McCollin Arnett
Murrell K. Glover
Arnold Koff
H. George Latham
Eugene E. Magat
James K. Rosser
Walter R. Whately
William Copulsky
David C. England
A. E. Montagna
William John Roberts
Edward George Samsa
Pelham Wilder
George M. Wyman
Don Martin Alstadt
Leon Freedman
Irving S. Goldstein
Tony M. Immediata
Arthur C. Bond
Waldo B. Ligett
Richard H. Loeppert
Barbara Roth
Edward Sherman
John E. Wilson
Robert A. Berntsen
Chester J. Cavallito
Carl E. Bryan
Raymond Cyrus White
Arthur R. Clark
Edgar J. Roberts
John N. Roper


November 2-3, 2007
Durham Technical Community College

Preliminary Information:

The theme of the 179th Meeting will be "Technology and Chemical Education." We are pleased to announce that our keynote speaker will be Dr. Jim Reeves from UNC-Wilmington, a leader in chemical education and distance learning. He is co-creator of the Anytime Anywhere Chemistry Experience distance learning laboratories, which can be found at

Call for Presenters:

We are currently looking for colleagues who would like to contribute to our program by giving a presentation or leading a workshop or round-table discussion. While the focus of the conference will be in the area of technology and distance learning, we strongly encourage topics from other areas to give us a diverse program. Current information on can be found at


Mark Matthews, Program Chair
Phone: 919-686-3773
Email: [email protected]


October 10, 2007
10:00 AM
Historic Jamestown


A plaque will be presented by Bruce Bursten, President-elect of the ACS, to designate Historic Jamestown as a National Historic Chemical Landmark.

Inquires, please contact:
Judah Ginsberg
American Chemical Society
1155 16th Street, NW
Washington, NC 20036

(202) 872-6274
(800) 227-5558
[email protected]


October 21-27, 2007

CHEMISTRY DAY at the NC Museum of Natural Sciences

Saturday, October 20, 2007, 10:00 am to 3:00 pm
"The Many Faces of Chemistry"

Chemical craziness at the Museum! Join in the fun and discover that chemistry is cool as the Museum and the American Chemical Society concoct a day full of awesome chemistry experiments, magic, exhibits, and special presentations. This year's theme is "The Many Faces of Chemistry."

General information about chemistry careers will be provided by area employers. The event will be held at the NC Museum of Natural Sciences in downtown Raleigh on Saturday, October 20, 2007 from 10:00 am to 3:00 pm. Museum information is available at:

Last year, over 2,400 people of all ages and backgrounds packed the museum exhibit hall to help deliver a positive message about the contributions of chemistry to our lives.

Please volunteer by contacting the Local Section's National Chemistry Week Coordinator, Meredith Storms at [email protected] or (910)521-6427


Use this link to stay up-to-date on meetings, workshops, short courses, and symposia both in the United States and abroad.


November 12-16, 2007
Durham, NC

Monday, November 10

Chemical Engineering & Process Fundamentals for Chemists
Essentials of Medicinal Chemistry & Pharmacology
Laboratory Safety
Project Management for Technical Professionals
Statistical Analysis of Laboratory Data

Wednesday, November 14, 2007

Effective Technical Writing (ETWR)
Analysis and Interpretation of Mass Spectral Data
Pharmacokinetics and Pharmodynamics
Methods Development & Validation Procedures in the Analytical Lab
Process Research in the Pharmaceutical Industry
Experimental Design for Productivity & Quality in R&D

Course Fees and Discounts


  • Two-day Courses - $995
  • Three Day Courses - $1345
  • ETWR Course - $885

Academic Member and FT Student Member*

  • Two-day Courses - $497.50
  • Three-day Courses - $672.50
  • ETWR Course - $442.50

*To receive the academic discount: register by fax or by phone at (202) 872-4508


  • Two-day Course - $1145
  • Three-day Course - $1445
  • ETWR Course - $985

Early Registration - Register before 10/1/07 and save $100 off the course fee

Late Registration: Register after 11/11/07 and pay a $100 administrative fee

Group Rate: Buy 4, Get one Free! Completing 5 registrations for any combination of participants and courses

Hotel Registration:
Hilton Durham
3800 Hillsborough Road
Durham, NC 27705

Reserve your room by October 12th and receive a special ACS Guest Room Rate of $132/night.

Check the ACS website for more details:


Scholarships will be awarded to undergraduate students who will be actively conducting research in the chemical sciences. The exact scholarship amount will depend on the number of awards. Please note that only undergraduate students within the North Carolina Local Section of the American Chemical Society are eligible.

Scholarship money can be used to supplement the needs of the student's work in the laboratory in the form of research reagents, copies, books, and computer software. The scholarship money may not be used for tuition or housing costs. Additionally, the scholarship winners and their advisors will be invited to dinner and networking with the NC ACS Local Section Executive Committee Members. The scholarship grant becomes available for work beginning as early as November 15, 2007 and expires before the start of the fall semester 2008.

Application deadline: Friday, October 26, 2007, 11:59 P.M.

Applicants are strongly encouraged to use the online scholarship application form found at the following url:

Previous scholarship winners are posted at:

Contact Bryce Chaney ([email protected]) for any questions concerning the application instructions or requirements.


[email protected]
James F. Brady, Ph.D. LLC

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  • Consultation on hapten, antibody and study design

  • Method validation and sample analysis in a good laboratory practices compliant environment

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  • Nineteen years of experience working with a variety of matrices in a regulatory context
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    Craig Langway, ext. 6771
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©2007 Waters Corporation Waters, ACQUITY UPLC and The Science of What's Possible are trademarks of Waters Corporation.

Executive Committee:

A. Tonelli (NCSU), Chair '07 515-6588 [email protected]
J. Brown, (Brown Law Office), Chair-Elect '08 522-0312 [email protected]
M. Pasquinelli, (NSCU), Secretary '07515-9426[email protected]
J. T. Bursey, Treasurer '05-'06493-3025[email protected]
N. S. Tulve (EPA), TH Editor '06-present541-1077[email protected]
K. E. Levine (RTI), TH Editor '03 to '06541-8886[email protected]
J. L. Chao (IBM), Councilor '06-'08 543-3054[email protected]
E. C. Bigham (GSK), Dir. District IV483-9844[email protected]
R. W. Morrison, Jr. (GSK,NCSU), Coun '05-'07515-2549[email protected]
L. Sremaniak (NCSU), Councilor, '04-'07515-2937[email protected]
A. L. Crumbliss (Duke), Councilor '07-'09660-1540[email protected]
R. A. Palmer (Duke), Councilor '07-'09660-1539[email protected]
R. M. Forbis (UNC), Alt. Councilor, '05-'07962-2096[email protected]
N. Oberlies (RTI), Alt. Councilor, '07-'09541-6958[email protected]
S. Paisner (Lord), Alt. Councilor, '06-'08 469-2500 (ext.2490) [email protected]
K. Tomer, (NIEHS), Alt. Councilor, '05-'07541-1966[email protected]
K. Lyle, (Duke), Alt. Councilor, '07-'09660-1621[email protected]
C. Goss (GSK), Past Chair '06483-9755[email protected]
S. Levine (NCSU, Ret.), Past Chair '05453-2653[email protected]
D. Coleman (BPCTi), Past Chair '04306-2239[email protected]
J. A. Myers (NCCU), Past Chair '03530-6461[email protected]
S.C.J. Sumner (RTI), Past Chair, '02541-7479[email protected]
C. M. Balik (NCSU), Past Chair, '01515-2126[email protected]
B. E. Sturgeon (NIEHS), Past Chair, '00  
G. H. Wahl, Jr. (NCSU), Past Chair '99515-2941[email protected]
M. M. Bursey (UNC), Ex Officio493-3025[email protected]
K. A. Cutler (NCCU) , Project Seed Ex Officio530-6172[email protected]
E. L. Eliel (UNC), Ex Officio962-6198[email protected]
K. Dawes (NCSU), PDG, Ex Officio469-2500dorian, [email protected]
S. Movassaghi (Bayer), TCDG, Ex Officio sherry.movasaghi@
T. M. O'Connell (GSK), TMRDG, Ex Officio483-1535[email protected]
B. N. Chaney (BD), Scholarship Chair[email protected]

Updated: October 14, 2007

North Carolina Section of the American Chemical Society
Send comments to: [email protected]

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